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mRNA distribution within cells is an important consideration in gene expression and developmental studies. The level of a particular mRNA species in a cell is a function of the rate of transcription and the rate of intracellular transport. The analysis of the distribution of subcellular mRNAs within mouse oocytes, and embryos, was undertaken. Both immunocytochemical and in situ hybridization techniques were employed.Using the orbit for Parkinson's disease.
Parkinson's disease (PD) is the most common neurodegenerative disorder. The deep brain stimulation (DBS) procedure is the surgical intervention to target a specific region of the brain which controls movement. The use of DBS in PD patients is increasing in the hope to improve their quality of life. The DBS is normally performed with the patient awake under the supervision of an anaesthetist, but there is growing concern that this could be associated with increased surgical risks and therefore a new technique, the awake unsupervised DBS (AUDS), is being used. This review will look at what effect AUDS has on patients and discusses other issues which are important to anaesthetists when they encounter the patient in the OR. 0b46394aab